Synthesis 2019; 51(06): 1435-1444
DOI: 10.1055/s-0037-1610332
paper
© Georg Thieme Verlag Stuttgart · New York

Metal-Free Synthesis of Biaryl- and Teraryl-Cored Diarylmethanes by Ring Transformation of 2H-Pyran-2-ones

Chemistry Division, School of Advanced Science, VIT University, Chennai Campus, Chennai 600127, Tamil Nadu, India   Email: fatehveer.singh@vit.ac.in
,
Priyanka B. Kole
› Author Affiliations
Further Information

Publication History

Received: 06 September 2018

Accepted after revision: 26 October 2018

Publication Date:
30 November 2018 (eFirst)

Abstract

An efficient metal-free approach for the synthesis of functionalized biaryl-cored diarylmethanes is described by the ring transformation of 2H-pyran-2-ones using 4-phenylbutan-2-one as carbanion source. Moreover, 2H-pyran-2-ones were reacted with 1,3-diphenylacetone in the presence of base to achieve functionalized teraryl-cored diarylmethanes. All the ring transformation reactions were performed under mild reaction conditions to afford the biaryl- and teraryl-cored reaction products in high yields.

Supporting Information

 
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