Improved One-Pot, Four-Component Strategy to Access ­Functionalized Dihydropyridines by Using 4-(N,N-Dimethylamino)pyridine as a Catalyst

Abstract

A convenient strategy has been developed for the synthesis of structurally diverse novel 1,4-dihydropyridine frameworks bearing a 3-nitrophenyl moiety through a one-pot, four-component reaction with 4-(N,N-dimethylamino)pyridine as a catalyst at room temperature. This tandem process proceeds more effectively than previous catalytic processes.

Key words

dimethylaminopyridine - nitrophenyldihydropyridines - multi­component reactions - nitriles - amines - organocatalysis

• References and Notes

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