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Synthesis 2018; 50(10): 2087-2093
DOI: 10.1055/s-0037-1609364
DOI: 10.1055/s-0037-1609364
paper
A Convenient and Concise Metal-Free Approach to Functionalized Bicyclic Pyrimidinones from Oxazine-2,6-diones
Authors
We thank Syngenta Research & Technology Centre, Goa for providing the research facility and thank the management for supporting this work.
Weitere Informationen
Publikationsverlauf
Received: 31. Januar 2018
Accepted after revision: 22. Februar 2018
Publikationsdatum:
20. März 2018 (online)
Abstract
The synthesis of previously unreported pyrazolo-pyrimidinones and isoxazolo-pyrimidinones are achieved via metal-free coupling of oxazine-2,6-diones with pyrazolidinone and isoxazolidinone, respectively. The synthesis provides easy access to a variety of novel 2-dimensional building blocks that can be derivatized to generate a range of drug- and agro-like molecules.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1609364.
- Supporting Information (PDF)
- CIF File (ZIP)
-
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