Synthesis 2018; 50(09): 1849-1856
DOI: 10.1055/s-0036-1591861
paper
© Georg Thieme Verlag Stuttgart · New York

Continuous-Flow Reductive Alkylation: Synthesis of Bio-based Symmetrical and Disymmetrical Ethers

Sophie Bruniaux
Sorbonne Universités, Université de Technologie de Compiègne, Centre de Recherche Royallieu, CS 60 319, 60203 Compiègne cedex, France   Email: christophe.len@utc.fr
,
Denis Luart
Ecole Supérieure de Chimie Organique et Minérale, EA 4297 TIMR, Compiègne, France
,
Sorbonne Universités, Université de Technologie de Compiègne, Centre de Recherche Royallieu, CS 60 319, 60203 Compiègne cedex, France   Email: christophe.len@utc.fr
PSL Research University, Chimie ParisTech, CNRS, Institut de Recherche de Chimie Paris, 11 rue Pierre et Marie Curie, 75231 Paris Cedex 05, France
› Author Affiliations
This work was performed in partnership with the SAS PIVERT within the frame of the French Institute for the Energy Transition (Institut pour la Transition Energetique (ITE)) P.I.V.E.R.T. (www.institut-pivert.com) selected as an Investment for the Future (Inves- tissements d’Avenir). This work was supported, as part of the Investments for the Future, by the French Government under reference ANR-001-01.
Further Information

Publication History

Received: 03 October 2017

Accepted after revision: 10 November 2017

Publication Date:
24 January 2018 (eFirst)

Abstract

For the first time, a reductive alkylation process in continuous flow has been elaborated for the conversion of bio-based alcohols and aldehydes into symmetrical and dissymmetrical high-value-added ethers for industrial companies. The developed method is an etherification associating liquid, solid and gas phases under green conditions (continuous flow, catalysis, bio-based starting materials).

 
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