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Synthesis 2018; 50(05): 1141-1151
DOI: 10.1055/s-0036-1591842
DOI: 10.1055/s-0036-1591842
paper
T3P® – A Benign Desulfurating Reagent in the Synthesis of Isothiocyanates
Autoren
The authors gratefully acknowledge financial support from the Polish National Science Centre (grant no. DEC 2011/03/B/ST5/01058).
Weitere Informationen
Publikationsverlauf
Received: 13. Oktober 2017
Accepted after revision: 02. November 2017
Publikationsdatum:
27. November 2017 (online)
Abstract
A number of alkyl, aryl and bifunctional isothiocyanates are obtained in moderate to high yields (41–94%) in a two-step, one-pot reaction of the parent primary amines or their salts with carbon disulfide, followed by reaction of the thus formed dithiocarbamates with T3P® (propane phosphonic acid anhydride) as a new and efficient desulfurating agent.
Key words
isothiocyanates - desulfuration - propane phosphonic acid anhydride (T3P®) - dithiocarbamates - amino acids - aminesSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591842.
- Supporting Information (PDF) (opens in new window)
-
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