Synthesis of Emindole SB
Received: 23 September 2016
Accepted after revision: 15 November 2016
23 November 2016 (eFirst)
Paxilline indole diterpenes have been a subject of scientific inquiry for over 30 years due to their diverse biological activities and unique structural features. These efforts resulted in a multitude of synthetic approaches and a dozen completed synthesis. Here, we discuss our contributions to this area that culminated in an 11-step synthesis of (±)-emindole SB.