Thieme Chemistry Journals Awardees – Where Are They Now?
Phospha-Münchnone 1,3-Dipolar Cycloaddition with Alkenes: A One-Pot Approach to 2-Pyrrolines from Imines, Acid Chlorides and Alkenes
Received: 03 October 2016
Accepted after revision: 07 November 2016
02 December 2016 (eFirst)
We describe herein studies on the cycloaddition of phospha-Münchnones and alkenes, and the factors that influence selectivity between 2-pyrrolines and bicyclic products. Coupling this cycloaddition with the formation of the dipoles can provide a one-pot route to synthesize 2-pyrrolines in moderate yield from imines, acid chlorides and alkenes.