Synlett 2016; 27(19): 2685-2688
DOI: 10.1055/s-0036-1588300
© Georg Thieme Verlag Stuttgart · New York

Synthesis of a Novel Rhizobitoxine-Like Triazole-Containing Amino Acid

Thibaut Boibessota, David Bénimèlisa, Marion Jeanb, Zohra Benfoddaa, Patrick Meffre*a
  • aUniversité de Nîmes, EA7352 CHROME, Rue du Dr G. Salan, 30021 Nîmes Cedex 1, France   Email:
  • bAix Marseille Univ, CNRS, Centrale Marseille, iSm2, Marseille, France
Further Information

Publication History

Received: 10 June 2016

Accepted after revision: 05 August 2016

Publication Date:
18 August 2016 (eFirst)


The synthesis of the four stereoisomers of a new 1,2,3-triazole analogue of rhizobitoxine from serine is described. The key step is a Huisgen 1,3-dipolar cycloaddition on an ethynylglycine synthon.

Supporting Information