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Synthesis 2016; 48(19): 3183-3198
DOI: 10.1055/s-0035-1562452
DOI: 10.1055/s-0035-1562452
paper
Diastereoselective Gold(I)-Catalyzed [2+2+2] Cycloaddition of Oxo-1,5-enynes
Further Information
Publication History
Received: 21 May 2016
Accepted after revision: 13 June 2016
Publication Date:
19 July 2016 (online)
‡ These authors contributed equally.
In memory of Professor Jean Normant.
Abstract
The intramolecular gold(I)-catalyzed [2+2+2] cycloaddition of oxo-1,5-enynes bearing protected homopropargylic alcohols provides access to oxatricyclic adducts with good to excellent diastereoselectivity.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1562452.
- Supporting Information
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For reviews on the total synthesis of natural products using gold(I) catalysis, see:
See our previous reports on the total synthesis of terpenoids using gold(I) catalysis: