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Synthesis 2016; 48(19): 3155-3164
DOI: 10.1055/s-0035-1561670
DOI: 10.1055/s-0035-1561670
paper
Orthogonally Reacting Boron Coupling Reagents: A Novel Multicomponent-Multicatalytic Reaction [(MC)2R] of Dichlorovinylpyrazine
Weitere Informationen
Publikationsverlauf
Received: 03. April 2016
Accepted after revision: 09. Mai 2016
Publikationsdatum:
21. Juni 2016 (online)
Abstract
The results presented herein illustrate the feasibility of two orthogonally reacting boron coupling reagents as a new control strategy in multicomponent-multicatalytic reaction [(MC)2R] chemistry. A process employing dichlorovinylpyrazine merging the rhodium-catalyzed hydroarylation with the Suzuki coupling has been discovered. Three new bonds are formed in a one-pot, one-step process efficiently providing highly substituted diaza-dihydrodibenzoxepine products.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1561670.
- Supporting Information
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