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Synfacts 2016; 12(2): 0118
DOI: 10.1055/s-0035-1561112
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of a Key Intermediate in the Manufacture of Tetracyclines

Authors

    Contributor(s):

  • Philip Kocienski

Further Information

Publication History

Publication Date:
19 January 2016 (online)

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Key words

tetracyclines - asymmetric addition - N-methylephedrine - chiral ligands - Ellman–Davis amine synthesis - tert-butanesulfinimides