Synthesis 2016; 48(04): 573-578
DOI: 10.1055/s-0035-1560544
paper
© Georg Thieme Verlag Stuttgart · New York

N-Heterocyclic Carbene Catalyzed Monoacylation of Vicinal Diols

Satoru Kuwano*
Faculty of Pharmaceutical Sciences, Daiichi University of Pharmacy, 22-1 Tamagawa-cho, Minami-ku, Fukuoka 815-8511, Japan   Email: [email protected]
,
Toshinobu Masuda
Faculty of Pharmaceutical Sciences, Daiichi University of Pharmacy, 22-1 Tamagawa-cho, Minami-ku, Fukuoka 815-8511, Japan   Email: [email protected]
› Author Affiliations
Further Information

Publication History

Received: 30 September 2015

Accepted after revision: 09 November 2015

Publication Date:
25 November 2015 (online)


Abstract

The N-heterocyclic carbene (NHC)-catalyzed monoacylation of vicinal diols is described. Monoacylated compounds of 1,2-, 1,3-, and 1,4-diols are obtained in good yields and selectivity under mild reaction conditions at ambient temperature.

Supporting Information

 
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