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Synlett 2016; 27(02): 241-244
DOI: 10.1055/s-0035-1560505
DOI: 10.1055/s-0035-1560505
letter
Synthesis of Tetrazole-Containing C-Phosphonoacetamidines
Authors
Weitere Informationen
Publikationsverlauf
Received: 21. August 2015
Accepted: 15. September 2015
Publikationsdatum:
20. Oktober 2015 (online)
Abstract
Addition of 5-substituted tetrazoles to dialkyl 2-(N-tert-butyl- or N-adamantyl)iminovinylphosphonates proceeds regioselectively to yield novel tetrazole-containing phosphonoacetamidines – 2-[(N-tert-butyl- or N-adamantyl)imino-2-(tetrazolyl)ethyl]phosphonic acid dialkyl esters – with good yields. The reactions occur via nucleophilic attack of the tetrazole N-1 atom at the C=C bond.
Key words
NH-tetrazoles - C-phosphonoketenimines - C-phosphonoamidines - imino phosphonates - phosphorylated acetamidinesSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1560505.
- Supporting Information (PDF)
-
References and Notes
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