Synlett 2014; 25(16): 2281-2284
DOI: 10.1055/s-0034-1378371
cluster
© Georg Thieme Verlag Stuttgart · New York

Regio- and Diastereoselective Nickel-Catalyzed Cycloaddition of Activated Cyclopropanes with Allenes

Authors

Further Information

Publication History

Received: 14 May 2014

Accepted after revision: 11 June 2014

Publication Date:
06 August 2014 (online)


Graphical Abstract

Preview

Abstract

Nickel-catalyzed intermolecular [3+2] cycloaddition of activated cyclopropanes with allenes has been developed. This transformation generates highly substituted five-membered carbocyclic compounds with good regio- and diastereoselectivity under mild reaction conditions. This reaction can be extended to a broad variety of allenes to obtain the corresponding adducts.

Supporting Information