Download PDF
Endoskopie heute 2013; 26(3): 203-207
DOI: 10.1055/s-0033-1350414
Originalarbeit
© Georg Thieme Verlag KG Stuttgart · New York

Neuerungen in der Videokapselendoskopie

New Developments in Capsule Endoscopy
I. Steinbrück
Further Information

Publication History

Publication Date:
09 October 2013 (online)

Also available at
    Permissions and Reprints

Zusammenfassung

In den 12 Jahren seit ihrer Einführung ist die Entwicklung der Videokapselendoskopie rasant vorangeschritten. Die Entwicklungen im Bereich der Hard- und Software haben zum Ziel, die Aufnahmekapazität zu verlängern, die diagnostische Güte zu verbessern, die Befundungsdauer zu verkürzen und dadurch die Arzt- und Patientenakzeptanz für die Methode zu erhöhen. Ein weiterer Fokus liegt auf der Erweiterung des Indikationsspektrums auf verschiedene Teile des Gastrointestinaltrakts. Innovationen für die Zukunft umfassen im Bereich der Software verschiedene Möglichkeiten zur digitalen Bearbeitung des Kapselfilms und im Bereich der Hardware die Entwicklung von Antriebs- und Steuerungssystemen sowie die Integration verschiedener Messsensoren und therapeutischer Implikationen. Darüber hinaus werden erste Ansätze für eine „Mouth-to-anus-Kapsel“ zur Visualisierung des gesamten Gastrointestinaltrakts verfolgt.

Abstract

Since the 12 years after its invention, the development of capsule endoscopy has evolved rapidly. The developments in the fields of hard- and software have been aimed to expand the recording capacity, to increase the diagnostic yield and thereby to enlarge the acceptance of this method both in physicians and patients. Secondly the expansion of indications to all parts of the GI tract is being focused. Innovations for the future contain various possibilities of digitally preprocessing of capsule films, the development of active locomotion and steering mechanisms as well as the integration of various built-in sensors and therapeutic implications into the capsule. Apart from that first attempts of a „mouth-to-anus“-capsule have been tested to visualize the whole GI tract.

Schlüsselwörter

Kapselendoskopie - adaptive Bildrate - FICE - Preprocessing - aktive Steuerung

Key words

capsule endoscopy - adaptive frame rate - FICE - preprocessing - active locomotion
 

  • Literatur

  • 1 Rokkas T, Papaxoinis K, Triantafyllou K et al. A meta-analysis evaluating the accuracy of colon capsule endoscopy in detecting colon polyps. Gastrointest Endosc 2010; 71: 792-798
    CrossrefPubMedGoogle Scholar
  • 2 Eliakim R, Yassin K, Metzger Y et al. Prospective multicenter performance evaluation of the second generation colon capsule compared with colonoscopy. Endoscopy 2009; 41: 1026-1031
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Cave DR, Fleischer DE, Leighton JA et al. A multicenter randomized comparison of the Endocapsule and the Pillcam SB. Gastrointest Endosc 2008; 68: 487-494
    CrossrefPubMedGoogle Scholar
  • 4 Hartmann D, Eickhoff A, Damian U et al. Diagnosis of small bowel pathology using paired capsule endoscopy with two different devices: a randomized study. Endoscopy 2007; 39: 1041-1045
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Kim HM, Kim YJ, Kim HJ et al. A pilot study of sequential capsule endoscopy using MiroCam and PillCam SB devices with different transmission technologies. Gut Liver 2010; 4: 192-200
    CrossrefPubMedGoogle Scholar
  • 6 Pioche M, Gaudin JL, Filoche B et al. Prospective, randomized comparison of two small-bowel capsule endoscopy systems in patients with obscure GI bleeding. Gastrointest Endosc 2011; 73: 1181-1188
    CrossrefPubMedGoogle Scholar
  • 7 Imagawa H, Oka S, Tanaka S et al. Improved detectability of small-bowel lesions via capsule endoscopy with computed virtual chromoendoscopy: a pilot study. Scand J Gastroenterol 2011; 46: 1133-1137
    CrossrefPubMedGoogle Scholar
  • 8 Duque G, Almeida N, Figueiredo P et al. Virtual chromoendoscopy can be a useful software in capsule endoscopy. Rev Esp Enferm Dig 2012; 104: 231-236
    CrossrefPubMedGoogle Scholar
  • 9 Kobayashi Y, Watabe H, Yamada A et al. Efficacy of flexible spectral imaging color enhancement on the detection of small intestinal diseases by capsule endoscopy. J Dig Dis 2012; 13: 614-620
    CrossrefPubMedGoogle Scholar
  • 10 Gupta T, Ibrahim M, Deviere J et al. Evaluation of Fujinon intelligent chromo endoscopy-assisted capsule endoscopy in patients with obscure gastroenterology bleeding. World J Gastroenterol 2011; 17: 4590-4595
    CrossrefPubMedGoogle Scholar
  • 11 Matsumura T, Arai M, Sato T et al. Efficacy of computed image modification of capsule endoscopy in patients with obscure gastrointestinal bleeding. World J Gastrointest Endosc 2012; 4: 421-428
    CrossrefPubMedGoogle Scholar
  • 12 Krystallis C, Koulaouzidis A, Douglas S et al. Chromoendoscopy in small bowel capsule endoscopy: Blue mode or Fuji Intelligent Colour Enhancement?. Dig Liver Dis 2011; 43: 953-957
    CrossrefPubMedGoogle Scholar
  • 13 Szczypinski PM, Sriram RD, Sriram PVJ et al. A model of deformable rings for interpretation of wireless capsule endoscopic videos. Medical Image Analysis 2009; 13: 312-324
    CrossrefPubMedGoogle Scholar
  • 14 Li B, Meng MQ, Xu L. A comparative study of shape features for polyp detection in wireless capsule endoscopy images. Conf Proc IEEE Eng Med Biol Soc 2009; 3731-3734
    PubMedGoogle Scholar
  • 15 Figueiredo PN, Figueiredo IN, Prasath S et al. Automatic Polyp Detection in Pillcam Colon 2 Capsule Images and Videos: Preliminary Feasibility Report. Diagn Ther Endosc 2011; 2011, Article ID 182435
    PubMedGoogle Scholar
  • 16 Charisis V, Hadjileontiadis LJ, Liatsos CN et al. Abnormal pattern detection in Wireless Capsule Endoscopy images using nonlinear analysis in RGB color space. IEEE, Eng Med Biol Soc 2010; 3674-3677
    PubMedGoogle Scholar
  • 17 Ciaccio EJ, Tennyson CA, Bhagat G et al. Classification of videocapsule endoscopy image patterns: comparative analysis between patients with celiac disease and normal individuals. Biomed Eng Online 2010; 9: 44
    CrossrefPubMedGoogle Scholar
  • 18 Mosse CA, Mills TN, Appleyard MN et al. Electrical stimulation for propelling endoscopes. Gastrointest Endosc 2001; 54: 79-83
    CrossrefPubMedGoogle Scholar
  • 19 Carpi F, Galbiati S, Carpi A. Controlled navigation of endoscopic capsules: concept and preliminary experimental investigations. Biomed Eng 2007; 54: 2028-2036
    PubMedGoogle Scholar
  • 20 Morita E, Ohtsuka N, Shindo Y et al. In vivo trial of a driving system for a self-propelling capsule endoscope using a magnetic field (with video). Gastrointest Endosc 2010; 72: 836-840
    CrossrefPubMedGoogle Scholar
  • 21 Swain P, Toor A, Volke F et al. Remote magnetic manipulation of a wireless capsule endoscope in the esophagus and stomach of humans (with videos). Gastrointest Endosc 2010; 71: 1290-1293
    CrossrefPubMedGoogle Scholar
  • 22 Keller J, Fibbe C, Volke F et al. Remote magnetic control of a wireless capsule endoscope in the esophagus is safe and feasible: results of a randomized, clinical trial in healthy volunteers. Gastrointest Endosc 2010; 72: 941-946
    CrossrefPubMedGoogle Scholar
  • 23 Keller J, Fibbe C, Volke F et al. Inspection of the human stomach using remote-controlled capsule endoscopy: a feasibility study in healthy volunteers (with videos). Gastrointest Endosc 2011; 73: 22-28
    CrossrefPubMedGoogle Scholar
  • 24 Ciuti G, Donlin R, Valdastri P et al. Robotic versus manual control in magnetic ering of an endoscopic capsule. Endoscopy 2010; 42 (02) 148-152
    Article in Thieme ConnectPubMedGoogle Scholar
  • 25 Valdastri P, Ciuti G, Verbeni A et al. Magnetic air capsule robotic system: proof of concept of a novel approach for painless colonoscopy. Surg Endosc 2012; 26 (05) 1238-1246
    CrossrefPubMedGoogle Scholar
  • 26 Rey JF, Ogata H, Hosoe N et al. Feasibility of stomach exploration with a guided capsule endoscope. Endoscopy 2010; 42: 541-545
    Article in Thieme ConnectPubMedGoogle Scholar
  • 27 Denzer UW, Rösch T, Hotayt B et al. Prospective Evaluation of magnetic gastric capsule examination (MGCE) in patients with indications for upper GI endoscopy. Endoscopy 2012; 44 (Suppl. 01) A60
    PubMedGoogle Scholar
  • 28 Ohta H, Katsuki S, Fujita T et al. A more patient friendly approach to a total gastrointestinal screening by single capsule endoscopy with navigation; using remote desktop control technology. Endoscopy 2012; 44 (Suppl. 01) A60
    PubMedGoogle Scholar
  • 29 Kim HM, Yang S, Kim J et al. Active locomotion of a paddling-based capsule endoscope in an in vitro and in vivo experiment (with videos). Gastrointest Endosc 2010; 72: 381-387
    CrossrefPubMedGoogle Scholar
  • 30 Sliker LJ, Kern MD, Schoen JA et al. Surgical evaluation of a novel tethered robotic capsule endoscope using micro-patterned treads. Surg Endosc 2012; 26: 2862-2869
    CrossrefPubMedGoogle Scholar
  • 31 Quirini M, Menciassi A, Scapellato S et al. Feasability proof of a legged locomotion capsule for the GI tract. Gastrointest Endosc 2008; 67: 1153-1158
    CrossrefPubMedGoogle Scholar
  • 32 Iddan GJ. Self propelled device. United states patent 6,958,034 B2, 2005
    PubMedGoogle Scholar
  • 33 Carta R, Tortora G, Thoné J et al. Wireless powering for a self-propelled and steerable endoscopic capsule for stomach inspection. Biosens Bioelectron 2009; 25: 845-851
    CrossrefPubMedGoogle Scholar
  • 34 Hatogai K, Hosoe N, Imaeda H et al. Role of Enhanced Visibility in Evaluating Polyposis Syndromes Using a Newly Developed Contrast Image Capsule Endoscope. Gut Liver 2012; 6 (02) 218-222
    CrossrefPubMedGoogle Scholar
  • 35 Ogata N, Ohtsuka K, Hayashi S et al. Evaluation of capsule endoscopy with image enhanced system (Contrast Capsule) for small intestinal lesions: a pilot study. Endoscopy 2012; 44 (Suppl. 01) A59
    PubMedGoogle Scholar
  • 36 Pandolfino JE, Schreiner MA, Lee TJ et al. Comparison of the Bravo wireless and digitrapper catheter-based pH monitoring systems for measuring esophageal acid exposure. Am J Gastroenterol 2005; 100: 1466-1476
    CrossrefPubMedGoogle Scholar
  • 37 Hsu L, Tang S, Huang W et al. An implantable, batteryless and wireless capsule with integrated impedance and pH sensors for detecting the reflux of acidic and non-acidic materials. Gastroenterology 2009; 136: W1080
    PubMedGoogle Scholar
  • 38 Johannessen EA, Wang L, Cui L et al. Implementation of multichannell sensors for remote biomedical measurements in a Microsystems format. IEEE Trans Biomed Eng 2004; 51: 525-535
    CrossrefPubMedGoogle Scholar
  • 39 Allison E, Kiraly Z, Springer G et al. Endocapsule. WO 2006/045011 A2. 2006;
    PubMedGoogle Scholar
  • 40 Rao SS, Kuo B, McCallum RW et al. Investigation of colonic and whole-gut transit with wireless motility capsule and radiopaque markers in constipation. Clin Gastroenterol Hepatol 2009; 7: 537-544
    CrossrefPubMedGoogle Scholar
  • 41 Clear NJ, Milton A, Humphrey M et al. Evaluation of the InteliSite capsule to deliver theophylline and frusemide tablets to the small intestine and colon. Eur J Pharm Sci 2001; 13: 375-384
    CrossrefPubMedGoogle Scholar
  • 42 Pithvala YK, Heizer WD, Parr AF et al. Use of the InteliSite capsule to study randitine absorption from various sites within the human intestinal tract. Pharm Res 1998; 15: 1869-1875
    CrossrefPubMedGoogle Scholar
  • 43 Wilding IR, Hirst P, Connor A. Development of a new engineering-based capsule for human drug absorption studies. Pharm Sci Tech Today 2000; 3: 385-392
    CrossrefPubMedGoogle Scholar
  • 44 Philips Technology. Philips intelligent pill technology. Available form: http://www.research.philips.com/newscenter/backgrounders/081111-ipill.html
    PubMedGoogle Scholar
  • 45 Van Der Schaar P, Broekhuizen-de GH, Nijsen J et al. Remotely controlled, small intestinal release of 99mtc-Pertechnetate using an ingestible electronic device: the IntelliCap. Endoscopy 2012; 44 (Suppl. 01) A60
    PubMedGoogle Scholar
  • 46 Kong K, Cha J, Jeon D et al. A rotational micro biopsy device for the capsule endoscope. Intelligent Robots and Systems. 2005 (IROS 2005). 2005 IEEE/RSJ International Conference, Aug 2-6, 2005, pp. 1839-1843 Available from: http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=1545441&isnumber=32977
    PubMedGoogle Scholar
  • 47 Uehara A, Hoshina K. Capsule endoscope NORIKA system. Minimum Invasive Ther Allied Technol 2003; 12: 227-234
    PubMedGoogle Scholar
  • 48 Kusuda Y. A further step beyond wireless capsule endoscopy. Sensor Rev 2005; 25: 259-260
    CrossrefPubMedGoogle Scholar