Synthesis 2014; 46(11): 1487-1492
DOI: 10.1055/s-0033-1340983
paper
© Georg Thieme Verlag Stuttgart · New York

Synthesis and Functionalization of 3-Azolylquinoxalin-2(1H)-ones

Oleksandr V. Geraschenko*
a  Enamine Ltd., Aleksandra Matrosova Street 23, Kyiv 01103, Ukraine
b  Department of Chemistry, Kyiv National Taras Shevchenko University, Volodymyrska Street 64, Kyiv 01033, Ukraine   Fax: +380(44)2351273   Email: Geraschenko.Aleksandr@gmail.com   Email: Pavel.Mykhailiuk@gmail.com
,
Pavel V. Khodakovskiy
a  Enamine Ltd., Aleksandra Matrosova Street 23, Kyiv 01103, Ukraine
b  Department of Chemistry, Kyiv National Taras Shevchenko University, Volodymyrska Street 64, Kyiv 01033, Ukraine   Fax: +380(44)2351273   Email: Geraschenko.Aleksandr@gmail.com   Email: Pavel.Mykhailiuk@gmail.com
,
Oleg V. Shishkin
c  STC, Institute for Single Crystals, National Academy of Science of Ukraine, 60 Lenina Ave., Kharkiv 61001, Ukraine
,
Andrey A. Tolmachev
a  Enamine Ltd., Aleksandra Matrosova Street 23, Kyiv 01103, Ukraine
b  Department of Chemistry, Kyiv National Taras Shevchenko University, Volodymyrska Street 64, Kyiv 01033, Ukraine   Fax: +380(44)2351273   Email: Geraschenko.Aleksandr@gmail.com   Email: Pavel.Mykhailiuk@gmail.com
,
Pavel K. Mykhailiuk*
a  Enamine Ltd., Aleksandra Matrosova Street 23, Kyiv 01103, Ukraine
b  Department of Chemistry, Kyiv National Taras Shevchenko University, Volodymyrska Street 64, Kyiv 01033, Ukraine   Fax: +380(44)2351273   Email: Geraschenko.Aleksandr@gmail.com   Email: Pavel.Mykhailiuk@gmail.com
› Author Affiliations
Further Information

Publication History

Accepted after revision: 21 February 2014

Received: 23 December 2013

Publication Date:
03 April 2014 (eFirst)

Abstract

Ethyl 2-azolylglyoxylates react smoothly with o-phenylenediamines and 1,2-diaminocyclohexane in acetonitrile at room temperature to give the corresponding 3-azolylquinoxalin-2(1H)-ones and their saturated analogues in good to excellent yields.

Supporting Information

 
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