Synlett 2014; 25(6): 863-865
DOI: 10.1055/s-0033-1340848
letter
© Georg Thieme Verlag Stuttgart · New York

The First Stereoselective Total Synthesis of the Immunosuppressive Decalin Derivative Monascusic Acid B[1]

Jayprakash Narayan Kumar
Natural Products Chemistry Division, CSIR–Indian Institute of Chemical Technology, Hyderabad 500 007, India   Fax: +91(40)27193198   Email: biswanathdas@yahoo.com
,
Biswanath Das*
Natural Products Chemistry Division, CSIR–Indian Institute of Chemical Technology, Hyderabad 500 007, India   Fax: +91(40)27193198   Email: biswanathdas@yahoo.com
› Author Affiliations
Further Information

Publication History

Received: 06 December 2013

Accepted after revision: 30 January 2014

Publication Date:
06 March 2014 (online)


Abstract

The first stereoselective total synthesis of the immunosuppressive decalin derivative monascusic acid B has been accomplished from (R)-(+)-pulegone involving Horner–Wadsworth–Emmons and Julia–Kocienski olefination reactions and Lewis acid catalyzed intramolecular Diels–Alder cyclization.

Supporting Information

 
  • References and Notes

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