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Synlett 2014; 25(3): 455-456
DOI: 10.1055/s-0033-1340480
DOI: 10.1055/s-0033-1340480
spotlight
2-Halobenzamides
Further Information
Publication History
Publication Date:
16 December 2013 (online)
Introduction
2-Halobenzamides are important precursors in organic synthesis to construct various heterocyclic compounds. They exhibit strong intermolecular N–H···O=C hydrogen bonding[1a] and therefore, most of them are crystalline solids in nature and can be stored for a long period of time. Most of the 2-halobenzamides are soluble in organic solvents, for example, in dichloromethane, chloroform, acetone, methanol, etc.
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References
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