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Synlett 2014; 25(2): 280-282
DOI: 10.1055/s-0033-1340347
DOI: 10.1055/s-0033-1340347
letter
A Tandem Conjugate Addition–Intramolecular Horner–Wadsworth–Emmons Olefination Approach to the Synthesis of Cyclopentene[c]chroman-2-ones and Cyclopent-1-enecarboxylates
Autoren
Weitere Informationen
Publikationsverlauf
Received: 25. Oktober 2013
Accepted after revision: 09. November 2013
Publikationsdatum:
06. Dezember 2013 (online)
Abstract
A strategically new approach to cyclopentene[c]chroman-2-ones and cyclopent-1-enecarboxylates by tandem Michael–Horner–Wadsworth–Emmons reaction of 2,5-hexanedione with 3-(diethoxyphosphoryl)coumarins is described. The products were obtained as single diastereoisomers in high yields.
Key words
Michael addition - Horner–Wadsworth–Emmons olefination - tandem reaction - annulations - 1,5,7-triazabicyclo[4.4.0]dec-5-eneSupporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information (PDF) (opens in new window)
Primary Data
- for this article are available online at http://www.thieme-connect.com/ejournals/toc/synlett
and can be cited using the following DOI: 10.4125/pd0053th.
- Primary Data (ZIP) (opens in new window)
-
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