Synlett 2014; 25(1): 81-84
DOI: 10.1055/s-0033-1340086
letter
© Georg Thieme Verlag Stuttgart · New York

Cyclometalated Iridium Complexes as Highly Active Catalysts for the Hydrogenation of Imines

Weijun Tang, Chunho Lau, Xiaofeng Wu, Jianliang Xiao*
  • Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD, UK   Fax: +44(151)7943588   Email: j.xiao@liv.ac.uk
Further Information

Publication History

Received: 20 August 2013

Accepted after revision: 04 October 2013

Publication Date:
06 November 2013 (eFirst)

Abstract

A robust cyclometalated iridium catalyst has been developed for highly effective hydrogenation of imines. With very low catalyst loading (down to 0.005%), good to excellent yields have been achieved for a range of substrates in a short reaction time under mild conditions, providing an easy, efficient protocol for making amines.