Synlett 2014; 25(1): 120-122
DOI: 10.1055/s-0033-1340053
letter
© Georg Thieme Verlag Stuttgart · New York

Copper-Catalyzed Protodecarboxylation and Aromatization of Tetrahydro-β-Carboline-3-Carboxylic Acids

Ramu Meesala, Mohd Nizam Mordi*, Sharif Mahsufi Mansor
  • Centre For Drug Research, Universiti Sains Malaysia, Minden, 11800 USM, Penang, Malaysia   Fax: +60(4)6568669   Email: mnizam@usm.my
Further Information

Publication History

Received: 03 September 2013

Accepted after revision: 30 September 2013

Publication Date:
12 November 2013 (eFirst)

Abstract

An efficient synthetic methodology has been developed to construct aromatic β-carbolines from tetrahydro-β-carboline-3-carboxylic acids by copper-promoted sequential decarboxylation and oxidative aromatization.

Supporting Information