One-Pot Synthesis of Nitriles from Aldehydes Catalyzed by Deep Eutectic 
Solvent

Umakant B. Patil; Suresh S. Shendage; Jayashree M. Nagarkar

doi:10.1055/s-0033-1339904

Synthesis, Inhaltsverzeichnis

Synthesis 2013; 45(23): 3295-3299
DOI: 10.1055/s-0033-1339904

paper

One-Pot Synthesis of Nitriles from Aldehydes Catalyzed by Deep Eutectic Solvent

Umakant B. Patil

Department of Chemistry, Institute of Chemical Technology, N. Parekh Marg, Matunga, Mumbai 400 019, India Fax: +91(22)33611020 eMail: jayashreenagarkar@yahoo.co.in eMail: jm.nagarkar@ictmumbai.edu.in

,

Suresh S. Shendage

Department of Chemistry, Institute of Chemical Technology, N. Parekh Marg, Matunga, Mumbai 400 019, India Fax: +91(22)33611020 eMail: jayashreenagarkar@yahoo.co.in eMail: jm.nagarkar@ictmumbai.edu.in

,

Jayashree M. Nagarkar*

Department of Chemistry, Institute of Chemical Technology, N. Parekh Marg, Matunga, Mumbai 400 019, India Fax: +91(22)33611020 eMail: jayashreenagarkar@yahoo.co.in eMail: jm.nagarkar@ictmumbai.edu.in

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Abstract

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Abstract

The choline chloride–urea (1:2) based deep eutectic mixture as an efficient and ecofriendly catalyst for the one-pot synthesis of nitriles from aldehydes under solvent-free conditions under both conventional and microwave irradiation; the products were obtained in good to excellent yields.

Key words

nitriles - deep eutectic solvent - aldehydes - hydroxylamine hydrochloride - microwave

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