Aerobic Oxidation of Propargyl Alcohol: A Convenient Method for the Synthesis of Propiolaldehyde

Abstract

Propiolaldehyde was prepared by the oxidation of propargyl alcohol using molecular oxygen as the oxidant under atmospheric pressure and room temperature in a decent yield. Compared to the previous method with CrO₃, such a protocol avoids the use of a stoichiometric amount of oxidant, and the workup procedure is much more eco-friendly and convenient affording a higher yield of the product.

Key words

propargyl alcohol - aerobic oxidation - iron nitrate - TEMPO - sodium chloride

• References

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