Recent Progress in the Synthesis of Functionalized β-Lactams through Transition-Metal-Catalyzed C(sp³)–H Amidation

Dedicate to Professor Li-Xin Dai on the occasion of his 90^th birthday

Abstract

Transition-metal-catalyzed C–H activation and C–N bond formation has become one of the most important methods to generate heterocycles. Herein, recent progress in the synthesis of functionalized β-lactams through Pd- and Cu-catalyzed intramolecular C(sp³)–H amidation is highlighted.

Key words

palladium - copper - β-lactams - amidation - directing groups

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