Synthesis 2014; 46(03): 357-367
DOI: 10.1055/s-0033-1338565
paper
© Georg Thieme Verlag Stuttgart · New York

Synthetic Studies towards an Advanced Precursor of the Jatrophane Diterpene Pl-4

Rita Fürst
Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090 Vienna, Austria   Fax: +43(1)427752101   Email: uwe.rinner@univie.ac.at
,
Christoph Lentsch
Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090 Vienna, Austria   Fax: +43(1)427752101   Email: uwe.rinner@univie.ac.at
,
Uwe Rinner*
Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090 Vienna, Austria   Fax: +43(1)427752101   Email: uwe.rinner@univie.ac.at
› Author Affiliations
Further Information

Publication History

Received: 22 October 2013

Accepted after revision: 31 October 2013

Publication Date:
27 November 2013 (online)


Abstract

Jatrophane diterpenes, isolated from members of the Euphorbiaceae­ plant family, constitute a class of biologically and structurally intriguing natural products. Herein, different strategies for the preparation of an advanced intermediate towards the total synthesis of the jatrophane diterpene Pl-4 are described. Key strategies for the elaboration of the jatrophane precursors include hydrometalation and radical reactions.

Supporting Information

 
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