An Efficient and Mild Synthesis of Tetrahydro-4H-indol-4-one Derivatives via a Domino Reaction in Water

Abstract

An efficient domino approach for the synthesis of tetrahydro-4H-indol-4-one derivatives has been established. The use of catalytic amount of l-proline in water at 60 °C makes it quite simple, more convenient, and environmentally benign.

Key words

tetrahydro-4H-indol-4-one - amines - cyclization - domino reaction - catalysis

• References


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