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Synlett 2013; 24(5): 587-590
DOI: 10.1055/s-0032-1318271
DOI: 10.1055/s-0032-1318271
letter
Z-Selective Dimerization of Aromatic Terminal Alkynes Catalyzed by an Iridium(I)–N-Heterocyclic Carbene–Phosphine System
Further Information
Publication History
Received: 10 January 2013
Accepted after revision: 30 January 2013
Publication Date:
18 February 2013 (online)
Abstract
The development of an iridium-catalyzed regio- and stereoselective dimerization process has enabled the formation of (Z)-enyne products. More specifically, low catalyst loadings of an iridium(I) complex, featuring a bulky N-heterocyclic carbene–phosphine ligand combination, has been successfully employed in this selective head-to-head dimerization of terminal alkynes via C–H activation.
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