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Synlett 2012; 23(20): 2947-2950
DOI: 10.1055/s-0032-1317621
DOI: 10.1055/s-0032-1317621
letter
Synthesis of Highly Functionalized 1,3-Oxathioles via an Unusual [4+1] Annulation of α,α'-Dioxothione with 1,2-Diaza-1,3-dienes
Further Information
Publication History
Received: 15.10.20120
Accepted: 23 October 2012
Publication Date:
16 November 2012 (online)
Abstract
The present method provides highly functionalized 1,3-oxathioles through an unusual base-promoted [4+1] annulation between α,α'-dioxothione, generated in situ from a phthalimide precursor, and 1,2-diaza-1,3-dienes. An intriguing scaffold comprised of spiro-fused oxathiole and pyrazolone components was also obtained in moderate yield.
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References and Notes
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For some recent examples, see:
For selected examples, see: