A Novel Synthesis of Thioglycolurils by Ring Contraction of 5,7-Dialkyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones
Received: 24 May 2012
Accepted after revision: 16 August 2012
05 September 2012 (eFirst)
A new synthetic route to (E)-1,3-dialkyl-4-(benzylideneamino)-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-ones (thioglycolurils), by a ring contraction reaction of 5,7-dialkyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones with aromatic aldehydes, has been developed.