Synlett 2012; 23(10): 1463-1466
DOI: 10.1055/s-0031-1291007
letter
© Georg Thieme Verlag Stuttgart · New York

Sonogashira Reactions of 2,3,4,5-Tetrabromofuran: Synthesis of 2,3,4,5-Tetraalkynylfurans, 2,3,5-Trialkynylfurans and 2,5-Dialkynylfurans

Authors

  • Imran Malik

    a   Institut für Chemie, Universität Rostock, Albert Einstein Str. 3a, 18059 Rostock, Germany
    b   Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad, Pakistan
  • Zeeshan Ahmad

    a   Institut für Chemie, Universität Rostock, Albert Einstein Str. 3a, 18059 Rostock, Germany
  • Sebastian Reimann

    a   Institut für Chemie, Universität Rostock, Albert Einstein Str. 3a, 18059 Rostock, Germany
    c   Leibniz-Institut für Katalyse an der Universität Rostock e.V., Albert Einstein Str. 29a, 18059 Rostock, Germany
  • Muhammed Nawaz

    a   Institut für Chemie, Universität Rostock, Albert Einstein Str. 3a, 18059 Rostock, Germany
  • Tamás Patonay

    d   Department of Organic Chemistry, University of Debrecen, 4032 Debrecen, Egyetem tér 1, Hungary
  • Peter Langer*

    a   Institut für Chemie, Universität Rostock, Albert Einstein Str. 3a, 18059 Rostock, Germany
    c   Leibniz-Institut für Katalyse an der Universität Rostock e.V., Albert Einstein Str. 29a, 18059 Rostock, Germany
Further Information

Publication History

Received: 21 March 2012

Accepted: 23 March 2012

Publication Date:
18 May 2012 (online)


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Abstract

2,3,4,5-Tetrabromofuran is transformed into a variety of alkynyl-substituted furans by regioselective Sonogashira cross-coupling reactions. In this context, the first 2,3,4,5-tetraalkynylfurans and 2,3,5-trialkynylfurans were prepared. 2,3,4,5-Tetraalkynylfurans and 2,5-dialkynyl-3,4-diarylfurans show interesting fluorescence properties.

Supporting Information