Synthesis 2012; 44(15): 2413-2423
DOI: 10.1055/s-0031-1290384
paper
© Georg Thieme Verlag Stuttgart · New York

Copper-Catalyzed Cross-Coupling of O-Alkyl Hydroxamates with Aryl Iodides

Tatyana Kukosha
Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga 1006, Latvia, Fax: +37167550338   eMail: martins@osi.lv
,
Nadezhda Trufilkina
Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga 1006, Latvia, Fax: +37167550338   eMail: martins@osi.lv
,
Sergey Belyakov
Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga 1006, Latvia, Fax: +37167550338   eMail: martins@osi.lv
,
Martins Katkevics*
Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga 1006, Latvia, Fax: +37167550338   eMail: martins@osi.lv
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received: 28. März 2012

Accepted after revision: 09. Mai 2012

Publikationsdatum:
19. Juni 2012 (online)


Abstract

N-Aryl-O-alkylhydroxamic acid derivatives were prepared by copper-catalyzed cross-coupling of hydroxamates with aryl iodides. The reaction conditions are compatible with standard hydroxy-protecting groups on the hydroxylamine moiety and are applicable to a broad range of coupling partners.

Supporting Information