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Synthesis 2012(3): 417-422  
DOI: 10.1055/s-0031-1289666
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Facile Multicomponent Reaction Involving Isoquinoline, Dimethyl Allenedicarboxylate, and 2-Oxo-1H-indol-3-ylidenes

Rejithamol Rajana, Beneesh Pattoorpadi Babua, Amit Kumara, Rony Rajan Paula, C. R. Sinua, Eringathodi Sureshb, Vijay Nair*a
a Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India
Fax: +91(471)2491712; e-Mail: vijaynair_2001@yahoo.com;
b Analytical Science Division, Central Salt and Marine Research Institute, Bhavanagar 364 002, India
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Publication History

Received 11 October 2011
Publication Date:
04 January 2012 (online)

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Abstract

Transient zwitterions generated from dimethyl allenedicarboxylate and isoquinoline were successfully intercepted with 2-oxo-1H-indol-3-ylidenes to result in a facile multicomponent reaction under mild conditions.

Key words

zwitterions - allenes - multicomponent reactions - indoles - isoquinoline

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