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Synfacts 2011(4): 0353-0353  
DOI: 10.1055/s-0030-1259637
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of (+)-Lyconadin A

Contributor(s): Steven V. Ley, Philippa B. Cranwell
T. Nishimura, A. K. Unni, S. Yokoshima, T. Fukuyama*
The University of Tokyo, Japan
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Publikationsdatum:
18. März 2011 (online)

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Significance

Lyconadin A was isolated in 2001 from the club moss Lycopodium complanatum and found to exhibit modest biological activity against some cancer cell lines. To date, two total syntheses have been reported by Smith and ­Sarpong, in 2007 and 2010, respectively.