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Synfacts 2011(3): 0243-0243
DOI: 10.1055/s-0030-1259411
DOI: 10.1055/s-0030-1259411
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Nominal Banyaside B
C. S. Schindler, L. Bertschi, E. M. Carreira*
ETH Zürich, Switzerland
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
16. Februar 2011 (online)
Significance
Banyaside B belongs to the aeruginosin family of serine protease inhibitors. The above synthesis targeted a proposed structural motif which, upon completion of the total synthesis, was found to be incorrect. NMR spectroscopy studies led to a structural revision of the glycosylation site (not shown).