Synlett 2010(19): 2928-2930  
DOI: 10.1055/s-0030-1259009
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

Unprecedented Elimination of Conjugated Phenylthioether Groups by Low-Valent Titanocene

Nigel Ribeiro*, Ludivine Fetzer, Stéphane Streiff, Laurent Désaubry
Laboratory of Therapeutic Innovation (UMR 7200), Université de Strasbourg and CNRS, 74 Route du Rhin, BP 24, 67401 Illkirch Cedex, France
Fax: +33(3)68854310; e-Mail: [email protected];
Further Information

Publication History

Received 26 August 2010
Publication Date:
14 October 2010 (online)

Abstract

The first thioether elimination reaction utilizing a low-valent titanocene has been discovered. This reaction occurs under mild conditions and affords stereospecifically a variety of dienes and styrenes. Our data suggest that this new reaction involves an intermediate of dimerization of titanocene as the reactant responsible for this elimination.

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