Condensed Oxaziridine-Mediated [3+2] Cycloaddition: Synthesis of Polyhetero-bicyclo Compounds

Abstract

Polyhetero-bicyclo compounds were synthesized by a regioselective [3+2]-cycloaddition reaction between stable condensed oxaziridines and alkenes, alkynes, and nitriles. These molecules showed considerable antimicrobial activity against several gram-positive bacteria.

Key words

condensed oxaziridines - polyhetero-bicyclo - regio­selectivity - [3+2] cycloaddition - bactericidal properties

References and Notes

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18

Commercially available compound.

20

Commercially available compound.