Synthesis of Kapakahine E

V. R. Espejo; J. D. Rainier

doi:10.1055/s-0030-1258714

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Synfacts 2010(11): 1214-1214
DOI: 10.1055/s-0030-1258714

Synthesis of Natural Products and Potential Drugs

Synthesis of Kapakahine E

Contributor(s): Steven V. Ley, Catherine F. Carter
V. R. Espejo, J. D. Rainier*
University of Utah, Salt Lake City, USA

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Publication History

Publication Date:
21 October 2010 (online)

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Significance

The kapakahine family of natural products was isolated from the marine sponge Cribrochalina olemda. Kapakahine E was shown to be active against P388 murine leukemia cells (IC₅₀ = 5.0 µg/mL).