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Synlett 2010(17): 2679-2680  
DOI: 10.1055/s-0030-1258588
SPOTLIGHT
© Georg Thieme Verlag Stuttgart ˙ New York

Synthetic Applications of Diethyl Ethoxymethylenemalonate

Roberta Katlen Fusco Marra*
Instituto de Química, Universidade Federal Fluminense, UFF, CEP 24020-150 Niterói, Rio de Janeiro, Brazil
e-Mail: katlenposorganica@yahoo.com.br;
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Publikationsdatum:
30. September 2010 (online)

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Introduction

Diethyl ethoxymethylenemalonate (EMME, Figure  [¹] ), a liquid with a boiling point of 279-281 ˚C, is a very versatile reagent, extensively used for the synthesis of heterocyclic systems. The main application of this reagent is its use in the Gould-Jacobs reaction.

Figure 1 EMME

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