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Synlett 2010(13): 2041-2044  
DOI: 10.1055/s-0030-1258540
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© Georg Thieme Verlag Stuttgart ˙ New York

Asymmetric CuH-Catalyzed 1,4-Reductions in Water at Room Temperature

Shenlin Huang, Karl R. Voigtritter, John B. Unger, Bruce H. Lipshutz*
Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA
Fax: +1(805)8938265; e-Mail: lipshutz@chem.ucsb.edu;
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Publication History

Received 18 June 2010
Publication Date:
02 August 2010 (online)

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Abstract

Taking advantage of micellar catalysis in water, asymmetric hydrosilylation reactions can now be conducted at ambient temperatures using water, and only water, as the global medium.

Key words

copper hydride - hydrosilylations - reduction - asymmetric catalysis - micellar catalysis - green chemistry

    References and Notes

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12

Lipshutz, B. H.; Ghorai, S. University of California, Santa Barbara, CA, in preparation. TPGS-750-M = polyoxyethanyl-α-tocopheryl succinate.