Synthesis 2011(7): 1055-1058  
DOI: 10.1055/s-0030-1258453
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Formal Synthesis of (R)-(+)-Lasiodiplodin

Yange Huang, Adriaan J. Minnaard*, Ben L. Feringa*
Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
Fax: +31(50)3634278; e-Mail: a.j.minnaard@rug.nl; e-Mail: b.l.feringa@rug.nl;
Further Information

Publication History

Received 22 November 2010
Publication Date:
01 March 2011 (eFirst)

Abstract

A catalytic approach is reported for the enantioselective synthesis of (R)-(+)-lasiodiplodin methyl ether using asymmetric hetero allylic alkylation as the key step.