Synthesis 2011(7): 1055-1058  
DOI: 10.1055/s-0030-1258453
© Georg Thieme Verlag Stuttgart ˙ New York

Formal Synthesis of (R)-(+)-Lasiodiplodin

Yange Huang, Adriaan J. Minnaard*, Ben L. Feringa*
Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
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Publication History

Received 22 November 2010
Publication Date:
01 March 2011 (eFirst)


A catalytic approach is reported for the enantioselective synthesis of (R)-(+)-lasiodiplodin methyl ether using asymmetric hetero allylic alkylation as the key step.