Synthesis 2011(2): 229-234  
DOI: 10.1055/s-0030-1258344
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Chromeno[3,4-b]quinolines: Electrophilic Aromatic Substitution under Heck Conditions

Andrew L. C. Morris, Yvette A. Jackson*
Department of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica, West Indies
Fax: +1(876)9771835; e-Mail: yvette.jackson@uwimona.edu.jm;
Further Information

Publication History

Received 15 September 2010
Publication Date:
26 November 2010 (eFirst)

Abstract

The palladium-mediated intramolecular coupling reaction of 2-[(3-substituted-phenoxy)methyl]quinolines for preparing chromeno[3,4-b]quinolines was explored. The results of the cyclizations gave convincing evidence for an electrophilic aromatic substitution mechanism under standard Heck conditions.

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