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Synthesis 2010(24): 4213-4220  
DOI: 10.1055/s-0030-1258329
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Efficient Preparation of Polyunsaturated and Functionalized Acetylenic Ketones from Alkynylmanganese Bromides

Gérard Cahiez*, Olivier Gager, Alban Moyeux, Blandine Laboue-Bertrand
SOSCOM, Unité CNRS - Université de Paris13 FRE3043, 74 Rue Marcel Cachin, 93017 Bobigny, France
Fax: +33(1)48387363; e-Mail: gerard.cahiez@univ-paris13.fr;
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Publikationsverlauf

Received 14 September 2010
Publikationsdatum:
15. November 2010 (online)

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Abstract

α,β-Acetylenic ketones are efficiently prepared, under mild conditions, by reacting alkynylmanganese compounds with acyl chlorides. The procedure is especially useful for preparing polyfunctionalized and polyunsaturated α,β-acetylenic ketones.

Key words

organomanganese - acylation - acetylenic ketones - acyl chlorides

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