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        Synthesis  2010(22): 3802-3810  
DOI: 10.1055/s-0030-1258314
   DOI: 10.1055/s-0030-1258314
PSP
© Georg Thieme Verlag
      Stuttgart ˙ New YorkDirect Addition of Functionalized Organozinc Reagents to Carbon Dioxide, Ketones, and Aldehydes in the Presence of MgCl2
Further Information
            
               
                  
                        
                              Received
                              22 September 2010 
                      
Publication Date:
22 October 2010 (online)
            
         
      
   Publication History
Publication Date:
22 October 2010 (online)

Abstract
A variety of functionalized organozinc reagents undergo smooth addition reactions at ambient temperature to carbon dioxide, ketones, and aldehydes in the presence of stoichiometric amounts of MgCl2. Several reactions were performed on a 20 mmol scale.
Key words
organozinc reagents - magnesium chloride - carbon dioxide - phenylacetic acid derivatives - addition reactions
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