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Synthesis 2010(20): 3467-3473  
DOI: 10.1055/s-0030-1257908
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Convenient Domino Synthesis of 4,9-Diphenyl-2,3-dihydro-1H-benzo[f]iso­indole Derivatives

Yi-min Hu*, Xian-gang Lin, Tao Zhu, Jing Wan, Yong-jie Sun, Quan-sheng Zhao, Tao Yu
Laboratory of Functional Molecular Solids, Ministry of Education and Anhui Key Laboratory of Molecular-Based Materials, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui, 241000, P. R. of China
Fax: +86(553)3883517; e-Mail: yiminhu@mail.ahnu.edu.cn;
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Publication History

Received 26 May 2010
Publication Date:
30 July 2010 (online)

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Abstract

The first examples are described of a convenient domino synthesis of 4,9-diphenyl-2,3-dihydro-1H-benzo[f]isoindole derivatives in a single operation by means of palladium-catalyzed cyclization of simple 1,6-diynes with aryl halides.

Key words

domino reactions - cyclizations - heterocycles - polycycles - isoindoles

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