Semin Respir Crit Care Med 2010; 31(1): 055-065
DOI: 10.1055/s-0029-1246285
© Thieme Medical Publishers

Long-Term Outcomes in Patients Surviving Acute Respiratory Distress Syndrome

M. Elizabeth Wilcox1 , Margaret S. Herridge2
  • 1Division of Pulmonary and Critical Care Medicine, Toronto Western Hospital, Toronto, Ontario, Canada
  • 2Division of Pulmonary and Critical Care Medicine, Toronto General Hospital, Toronto, Ontario, Canada
Further Information

Publication History

Publication Date:
25 January 2010 (online)

ABSTRACT

Recent studies have begun to describe the long-term outcomes of acute respiratory distress syndrome (ARDS) survivors. These patients experience several physical, mental, and psychological morbidities that significantly impair their health-related quality of life (HRQL). Persistent for years after hospital discharge, decrements in functional and neuropsychological outcomes result in lost savings, employment reduction, and a reduction in HRQL among survivors and their caregivers. Future research should focus on the early identification of patients and their family members at risk for long-term sequelae, the mechanisms of injury leading to long-term ARDS consequences, and therapeutic modalities designed to prevent or decrease these morbidities. Clinicians, caregivers, and patients should be made aware of the deleterious long-term effects of the intensive care unit stay because they are currently poorly recognized and potentially modifiable.

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M. Elizabeth WilcoxM.D. 

Division of Pulmonary and Critical Care Medicine, Toronto Western Hospital

McLaughlin Wing 2-411P, 399 Bathurst St., Toronto, Ontario M5T 2S8, Canada

Email: elizabeth.wilcox@uhn.on.ca

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