Klinische Daten zum Einsatz von selenase^® bei Sepsis

Schlüsselwörter

Ischämie - Reperfusion - Natrium-Selenit

Keywords

ischemia - reperfusion - sodium selenite

Literatur

• 1 Angstwurm M WA, Engelmann L, Zimmermann T H. et al . Selenium in intensive care (SIC) study: Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock.  Crit Care Med. 2007;  35 118-126
• 2 Brigelius-Flohé R, Banning A, Schnurr K. Selenium-dependent enzymes in endothelial cell function.  Antioxid Redox Signal. 2003;  5 205-215
• 3 Dellinger R P. et al . Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008.  Crit Care Med. 2008;  36 296-327
• 4 Forceville X. Effects of high doses of selenium, as sodium selenit, in septic shock patients a placebo-controlled, randomized, double-blind, multi-center phase II study – Selenium and Sepsis.  J Trace Elem Med Biol. 2007;  21 (Suppl 1) 62-65
• 5 Gärtner R, Angstwurm M WA, Schottdorf J. Selensubstitution bei Sepsispatienten. Eine prospektiv randomisierte Studie.  Med Klinik. 1997;  92 12-14
• 6 Gründling M, Rickert S, Saeger D. et al . Acute high-dose sodium selenite administration improves intestinal microcirculation without affecting cytokine release in experimental endotoxemia.  J Trace Elem Med Biol. 2008 (submitted); 
• 7 Heyland D K, Dahliwal R, Suchner U, Berger M M. Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient.  Intens Care Med. 2005;  31 327-337
• 8 Horváthová M, Jahnová E, Gazdík F. Effect of selenium supplementation in asthmatic subjects on the expression of endothelial cell adhesion molecules in culture.  Biol Trace Elem Res. 1999;  69 15-26
• 9 Hou J C, Jiang Z Y, He Z F. [Inhibitory effect of selenium on complement activation and its clinical significance.  Zhonghua Yi Xue Za Zhi. 1993;  73 645-646
• 10 Jeong D W, Yoo M H, Kim T S, Kim J H, Kim I Y. Protection of mice from allergen-induced asthma by selenite: prevention of eosinophil infiltration by inhibition of NF-kappa B activation.  J Biol Chem. 2002;  277 17871-17876
• 11 Lehmann C, Egerer K, Weber M. et al . [Effect of selenium administration on various laboratory parameters of patients at risk for sepsis syndrome.  Med Klin (Munich). 1997;  92 (Suppl 3) 14-16
• 12 Mishra V, Baines M, Perry S E. et al . Effect of selenium supplementation on biochemical markers and outcome in critically ill patients.  Clin Nutr. 2007;  26 41-50
• 13 Vitoux. et al . Low plasma selenium in patients admited in an intensive care unit is related to systemic inflammatory response syndrome.  In: Nève et al, ed Therapeutic use of trace elements. Therapeutic use of trace elements. Plenum Press New York; 1996: 127-131
• 14 Zhang F, Yu W, Hargrove J L. et al . Inhibition of TNF-alpha induced ICAM-1, VCAM-1 and E-selectin expression by selenium.  Atherosclerosis. 2002;  161 381-386
• 15 Zimmermann T, Albrecht S, Kühne H, Vogelsang U, Grützmann R, Kopprasch S. [Selenium administration in patients with sepsis syndrome. A prospective randomized study.  Med Klin (Munich). 1997;  92 (Suppl 3) 3-4