Palladium-Catalyzed Dioxygenation of Alkenes

Significance

This work examines a palladium-catalyzed dioxygenation of alkenes under an air atmosphere. Several examples of analogous ­dioxygenations have recently emerged from the groups of Sigman (J. Am. Chem. Soc. 2009, 131, 17074), Dong and Song (J. Am. Chem. Soc. 2008, 130, 2962), and Jiang (J. Am. Chem. Soc. 2009, 131, 3846). This work is significant since ­atmospheric oxygen is the sole oxidant utilized throughout the reaction. The scope is general in substitution at the oxime (R^¹).