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Synthesis 2010(7): 1176-1080
DOI: 10.1055/s-0029-1219228
DOI: 10.1055/s-0029-1219228
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Concise Access to Pyrimidine-Annulated Azepine and Azocine Derivatives by Ruthenium-Catalyzed Ring-Closing Metathesis
Weitere Informationen
Received
24 November 2009
Publikationsdatum:
20. Januar 2010 (online)
Publikationsverlauf
Publikationsdatum:
20. Januar 2010 (online)
Abstract
Synthetic approaches to five- and six-membered-ring systems are commonly undertaken through cyclization and cycloaddition reactions, but the formation of seven- and eight-membered-ring systems are not as abundant. An efficient and high-yielding method for the synthesis of seven- and eight-membered-ring nitrogen-containing heterocycles by ring-closing metathesis is reported.
Keywords
uracil - azepine - azocine - ring-closing metathesis
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