Synthesis 2010(15): 2631-2635  
DOI: 10.1055/s-0029-1218827
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Direct Oxidative Conversion of Alcohols, Amines, Aldehydes, and Benzyl Halides into the Corresponding Nitriles with Trichloroisocyanuric Acid in Aqueous Ammonia

Hojat Veisi*
Department of Chemistry, Payame Noor University (PNU), Songhor, Kermanshah, Iran
Fax: +98(838)4227463; e-Mail: hojatveisi@yahoo.com;
Further Information

Publication History

Received 18 February 2010
Publication Date:
18 June 2010 (online)

Abstract

A new and efficient procedure for the one-pot conversion of various alcohols, aldehydes and primary amines into the corresponding nitriles in excellent yields was easily achieved by trichloro­isocyanuric acid (TCCA) as an oxidant and reagent in aqueous ammonia. Also, various benzylic halides were smoothly and directly converted into the corresponding aromatic nitriles in high yields under the same conditions.

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