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Synthesis 2010(10): 1629-1632  
DOI: 10.1055/s-0029-1218723
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Bromination of Aromatic Compounds Using Ammonium Bromide and Oxone®

Macharla Arun Kumar, Chozhiyath Nappunni Rohitha, Shivanand Janardhan Kulkarni, Nama Narender*
Catalysis Group, Indian Institute of Chemical Technology, Hyderabad 500007, India
Fax: +91(40)27160387; Fax: +91(40)27160757; e-Mail: narendern33@yahoo.co.in;
Further Information

Publication History

Received 15 February 2010
Publication Date:
06 April 2010 (online)

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Abstract

A simple, efficient and mild method for the selective bromination of activated aromatic compounds using ammonium bromide as the source of bromine and Oxone® as the oxidant in methanol or water as solvent is reported. The reaction proceeds at ambient temperature in yields ranging from moderate to excellent without a catalyst.

Key words

bromination - aromatic compounds - ammonium bromide - Oxone® - selectivity

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